ENEA European Postgraduate Course
Neuroendocrinology of Reproduction
From Puberty to Fertility and Menopause
October 1–2, 2026
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Organizing Committee
ENEA Neuroendocrinology of Reproduction Working Group
- Prof. Nelly Pitteloud – Chair & Course Director
University of Lausanne / CHUV
Switzerland - Dr Fanny Chasseloup
Postdoctoral Fellow
Montreal, Canada - Prof. Josanne Vassallo
University of Malta Medical School
Malta - Prof. Paraskevi Xekouki
University of Crete
Heraklion, Greece
Faculty
- Prof. Jacques Young
Université Paris-Saclay
France - Prof. Waljit Dhillo
Imperial College London
United Kingdom - Prof. Ali Abbara
Imperial College London
United Kingdom - Prof. Rebecca Campbell (TBC)
University of Otago
New Zealand - Prof. Elisabet Stener-Victorin (TBC)
Karolinska Institutet
Stockholm, Sweden - Prof. Sasha Howard
Queen Mary University of London
Barts Health NHS Trust.
London, United Kingdom - Prof. Taneli Raivio
University of Helsinki
Finland - Dr Richard Quinton
Imperial College London
United Kingdom - Prof. Duarte Pignatelli
University of Porto
Portugal - Prof. Sophie Christin-Maître
Sorbonne Université
Hôpital Saint-Antoine, AP-HP
Paris, France - Prof. Nelly Pitteloud
University of Lausanne / CHUV
Switzerland
PROGRAMME
Day 1
Puberty and Hypothalamic Reproductive Disorders
08:45 – 09:00
Opening Remarks
Prof. Nelly Pitteloud
09:00 – 09:45
Interrogating the GnRH Neuronal Network in Clinical Practice: The Role of Kisspeptin
Prof. Ali Abbara
Imperial College London
Topics
- Regulation of GnRH secretion
- Kisspeptin physiology
- Clinical applications in reproductive disorders
09:45 – 10:30
Central Precocious Puberty
Prof. Sasha Howard
Queen Mary University of London
Topics
- Neuroendocrine control of pubertal timing
- Diagnosis and management of central precocious puberty
10:30 – 10:45
Break
10:45 – 11:30
Delayed Puberty: Diagnostic Approach and Genetic Causes
Prof. Taneli Raivio (TBC)
University of Helsinki
Topics
- Constitutional delay of growth and puberty
- Differentiating CDGP from CHH
- Genetic causes of delayed puberty
11:30 – 12:15
Clinical and Genetic Spectrum of Congenital Hypogonadotropic Hypogonadism
Prof. Jacques Young
Université Paris-Saclay
Topics
- Kallmann syndrome and normosmic CHH
- Genetic architecture and clinical presentation
12:15 – 13:15
Lunch Break
13:15 – 14:00
Induction of Fertility in Hypogonadotropic Hypogonadism
Prof. Nelly Pitteloud
University of Lausanne / CHUV
Topics
- Pulsatile GnRH therapy
- Gonadotropin therapy
- Fertility outcomes
14:00 – 15:00
Interactive Clinical Case Discussion
Moderator:
Dr Richard Quinton
Imperial College London
Cases may include
- Delayed puberty
- Congenital hypogonadotropic hypogonadism
- Primary amenorrhea
15:00 – 15:15
Break
15:15 – 16:00
Discussion and Wrap-Up Day 1
Day 2
Reproductive Neuroendocrine Disorders in Adult Life
08:45 – 09:00
Welcome and Recap
Prof. Nelly Pitteloud
09:00 – 09:45
Neuroendocrine Mechanisms of Hot Flashes and NK3 Receptor Antagonists
Prof. Waljit Dhillo
Imperial College London
Topics
- Hypothalamic thermoregulation
- Neurokinin B signaling
- NK3 receptor antagonists
09:45 – 10:30
Neuroendocrine Mechanisms in Polycystic Ovary Syndrome
Prof. Rebecca Campbell (TBC)
University of Otago
Topics
- Neuroendocrine disruptions in PCOS
- Implications for patients
10:45 – 11:30
Metabolic Regulation of the Reproductive Axis and Obesity-Related Hypogonadism
Prof. Ali Abbara
Imperial College London
Topics
- Metabolic control of GnRH neurons
- Obesity and reproductive dysfunction
- Clinical implications
11:30 – 12:15
Translational Mechanisms of PCOS: Insights from Human and Animal Studies
Prof. Elisabet Stener-Victorin (TBC)
Karolinska Institutet
Stockholm, Sweden
Topics
- Translational PCOS models
- Neuroendocrine and metabolic mechanisms
12:15 – 13:15
Lunch Break
13:15 – 14:00
Functional Hypothalamic Amenorrhea: Pathophysiology and Diagnosis
Prof. Jacques Young
Université Paris-Saclay
Hôpital Bicêtre, Paris
Topics
- Hypothalamic suppression of the reproductive axis
- Diagnostic approach and differential diagnosis
14:00 – 14:45
Fertility Management in Functional Hypothalamic Amenorrhea
Prof. Sophie Christin-Maître
Sorbonne Université
Hôpital Saint-Antoine, AP-HP
Paris
Topics
- Pulsatile GnRH pump therapy
- Ovulation induction and pregnancy outcomes
14:45 – 15:00
Break
15:00 – 16:00
Interactive Clinical Case Session
Moderator:
Prof. Duarte Pignatelli
University of Porto, Portugal
Cases may include
- FHA vs PCOS
- Hypogonadotropic hypogonadism
- Infertility management
16:00 – 16:15
Course Wrap-Up
Prof. Josanne Vassallo
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